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Researchers trial new technology to detect dementia in adults with Down Syndrome

A research pilot supported by the NIHR Applied Research Collaboration (ARC) North East and North Cumbria will trial new technology that could help to detect the development of Alzheimer’s disease in adults with Down Syndrome.

Adults with Down Syndrome are at very high risk of developing Alzheimer’s disease, often much earlier than the general population. However, many people with Down Syndrome do not have access to specialist services that can monitor early changes in sleep, movement or memory that might point to the development of the disease.

Traditional tests, like overnight sleep studies or walking assessments in clinics, can be also uncomfortable, stressful or simply unrealistic for many people.

The project will explore whether SmartSocks, a soft pair of socks with tiny built‑in sensors, could offer a more comfortable and practical way to track sleep and walking patterns at home.

The trial is supported by Milbotix Ltd, a UK-based health technology company that developed SmartSocks. Milbotix are supplying the SmartSocks that will be used in the study.

The work will be led by Dr Tamlyn Watermeyer from Northumbria University, who is a Dementia Research Fellow supported by the NIHR ARC North East and North Cumbria.

An alternative to traditional tests

The study will work with 10 – 15 adults with Down Syndrome who will wear SmartSocks for up to five days in their usual home or supported‑living environment. Carers will help by keeping short notes about sleep, naps, falls or unusual behaviours. The aim is to understand whether people find the socks comfortable, whether they can be worn reliably, and whether the data they produce is clear enough to be useful.

The pilot will also create easy‑to‑use instructions and training materials, helping ensure that any future use of SmartSocks is shaped by the needs and preferences of people with Down Syndrome and the people who care for them.

Dr Watermeyer said: “People with learning disabilities, particularly those with Down Syndrome, are at much higher risk of developing dementia, yet are often diagnosed late or inaccurately.

“This work could enable earlier support and planning and reduce distress for individuals and families by improving access to appropriate care and offering personalised interventions. Ultimately, this research could benefit people with learning disabilities, carers, clinicians, and service providers, while also informing dementia research in the wider population.”

Read more about the work